Medication Switching Guide
For educational purposes only — a decision-support tool, not a substitute for clinical judgment.
Select a current medication and a target medication to see an evidence-based switching protocol with visual cross-taper timeline, interaction alerts, and clinical guidance. Every recommendation traces to a published source.
Related tools: Washout Period Calculator · Equivalent Dose Calculator · Drug Comparison Tool · Drug Reference
Disclaimer: This tool provides general switching guidance based on published evidence and should not replace clinical judgment. Individual patient factors (renal/hepatic function, comorbidities, concurrent medications, prior response) may necessitate modifications. Always monitor patients carefully during medication transitions.
Switching protocols: Keks NA, Hope J, Keogh S. Switching and stopping antidepressants. Australian Prescriber 2016;39(3):76-83 (PMID: 27346915) · NICE Guideline NG222 (2022) · Maudsley Prescribing Guidelines in Psychiatry, 15th Edition (2025). Drug pharmacokinetics, dose ranges, and tablet strengths from FDA prescribing information.
For prolonged-treatment tapers: The cross-tapers shown here use linear percentage steps over 2–4 weeks — the traditional approach in published guidelines. For patients on antidepressants for >6–12 months, slower “hyperbolic” tapers based on receptor-occupancy curves (Horowitz MA, Taylor D. Lancet Psychiatry 2019;6:538-546, PMID 30850328) may reduce withdrawal symptoms. Royal College of Psychiatrists tapering guidance (2020) and Davies & Read 2019 (PMID 30292574) provide further context on antidepressant withdrawal severity and incidence.